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Filed under Canadian pharmacy, Quinolones

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Norfloxacin, or Noroxin, was approved for use in urinary tract infection and where high concentrations are developed locally – prostatic infection, infectious diarrhea, because you are taking it orally, it is poorly absorbed, blood levels are low and that is why it is not used for any other kind of systemic infection. So it works in the gut, it is concentrated in the prostate and it is concentrated in the urine, but it really is more of a historical drug than anything else, because of its very poor blood levels. The dose is 400 mg twice a day. I still use it for urinary tract infections, because it doesn’t give good blood levels and therefore is less likely to cause central nervous system toxicity. The only side effects from norfloxacin are the GI and central nervous system – headache, dizziness, depression. Seizures are very uncommon, if they ever occur, because the blood levels are so poor. That may be an advantage in the treatment of urinary tract infection. Viagra super active online ed medications.
Ciprofloxacin, which was the second one released, is still an excellent drug. It has excellent activity against gram-negative bacilli, including pseudomonas. It is approved for urinary tract infection and pneumonia, but should not be used for pneumococcal pneumonia, even though it has been in the past, because the pneumococci are very borderline sensitive. It is approved for infectious diarrhea, infections caused by gram-negative bacilli of skin, skin structures, bones and joints. It is approved in use with gonorrhea, where it is very effective. It is useful in prostatic infection caused by gram-negative bacilli and virtually any gram-negative bacillus infection anywhere in the body. It is really the only quinolone that is highly active against pseudomonas. The dose varies from 250 to 750 mg twice a day and IV 200 to 400 mg twice a day. The adverse reactions are the simple quinolone side effects – GI and central nervous system. There have also been occasional seizures reported with ciprofloxacin, because it does get reasonable blood levels. Canadian cialis
I would have no use for either lomefloxacin or enoxacin. These are ciprofloxacin-like drugs that are supposed to do the same thing as ciprofloxacin and they do have the same activity as ciprofloxacin with the exception of pseudomonas, where these are not active. The doses are 400 mg of lomefloxacin, whose claim to fame is that it has a longer half life, so you just give it once a day, and enoxacin, which is given in the same dose basically as ciprofloxacin, 400 mg twice a day. But there are more side effects with these drugs. Lomefloxacin is one of the worst in terms of photosensitivity. They both have the same GI and central nervous system side effects that ciprofloxacin does. So with the exception of the ability to give lomefloxacin once a day as opposed to giving ciprofloxacin twice a day, there are no advantages of these drugs, and there are disadvantages. For example, enoxacin is the one that has the most interaction with theophylline, raising theophylline blood levels, much more so than ciprofloxacin. In my personal opinion, I see no real advantage for these two drugs.

Comments (0) Posted by Canadian Pharmacy on Wednesday, October 22nd, 2008

Filed under Canadian pharmacy, Drugs & medications

Online Pharmacy Safety Providing Erectile Dysfunction Drugs
Should you buy erectile dysfunction and impotence treatment drugs online?
Online Internet shopping today offers many benefits. You can research a product in the privacy of your own home and purchase most anything by clicking a mouse. But should we be allowed to buy prescription drugs via the Internet, bypassing a traditional office visit or conversation with a physician? In the August issue of Mayo Clinic Proceedings, researchers from Utah and several colleagues compare the relative safety of two systems — an online prescribing service versus traditional physician consultation – for patients seeking medication to treat erectile dysfunction. Viagra pofessional online.
Online prescribing, also called e-medicine prescribing, is relatively new in the United States. Patient demand for these services appears to be growing, but the researchers acknowledge that the health care industry “has appropriately raised serious concerns about the safety of prescribing over the Internet.” In 2002, the state of Utah signed a contract with an Internet prescribing service to prescribe erectile dysfunction drugs called PDE-5 inhibitors. Erectile dysfunction (ED) is the inability of a man to maintain a firm erection long enough to have sex. Canadian pharmacy erectile dysfunction medications.
The researchers randomly selected 1,000 patient medical records from patients seeking ED treatment from Jan. 1, 2001 to Dec. 31, 2005. Half (500) of these patients used the online prescriber (the e-medicine group), and 500 consulted a physician (the traditional medicine group) for treatment.
Using statistical analyses, the researchers compared the safety of both approaches — e-medicine versus traditional medicine — in treating patients who have ED. The safety comparisons looked at a number of criteria, including prescription appropriateness, how often the prescribers used a diagnostic tool called the International Index of Erectile Questions (IIEQs) and the level of patient education provided by prescribers.
Evaluating both systems for these safety criteria, the researchers concluded that the e-medicine system “outperformed the traditional system in most of the safety variables tested.” One area the e-medicine system appeared to excel was patient education. The authors noted that 100 percent of the e-medicine clients received written manufacturer product information, and 75.2 percent of e-medicine clients received tailored electronic messages. In comparison, study data showed that no medication instructions were recorded for 51.8 percent of patients who received prescriptions via a traditional physician consultation. Cheap levitra 20 mg.
“Innovation, technology and current medical practice all factor into the outcome of this study,” note the authors. “Application of an expert interview system specifically targeted to erectile dysfunction along with a continuous platform for patient client-physician communications make this particular Internet system comparable to traditional medical practice.”
The researchers acknowledge that additional research is needed to confirm these results. They also recommend that state regulatory agencies “consider using the regulatory model of oversight protections implemented by the state of Utah to license Internet prescribing companies.”
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Comments (0) Posted by Canadian Pharmacy on Saturday, October 4th, 2008